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Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms

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Treatment of Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Treatment of Neurodevelopmental Disorders by Randi Jenssen Hagerman,Robert L. Hendren Book Summary:

This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.

Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders by Gupta, Sanjeev Kumar,Venkatesan, Srinivasan,Goswami, S.P.,Kumar, Rajeev Book Summary:

Neurodevelopmental disorders encompass a group of conditions that can typically manifest during early childhood. These include intellectual disabilities, communication disorders, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), specific learning disorder (SLD), and motor disorders. Early identification and assessment can be a valuable tool in determining diagnosis, prognosis, functional abilities, and formulating clinical intervention for both children and adults with neurodevelopmental disorders. Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders is an essential reference source that discusses and disseminates contributions covering recent trends in diagnosis, assessment, and intervention techniques. Featuring research on topics such as clinical linguistics, neural connectivity, and animal-assisted therapy, this book is ideally designed for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neural and developmental disorder identification and strategies for clinician support and therapies.

The Human Frontal Lobes, Third Edition

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

The Human Frontal Lobes, Third Edition by Bruce L. Miller,Jeffrey L. Cummings Book Summary:

"Subject Areas/Keywords: brains, cognitive, diseases, dysfunctions, executive functions, frontal-subcortical circuits, frontotemporal dementia, human frontal lobes, lesions, mental disorders, networks, neuroanatomy, neurological, neurology, neuronal pathways, neuropsychiatric disorders, neuropsychological assessments, neuropsychology, neuroscience, normal aging, prefrontal cortex DESCRIPTION This authoritative work, now thoroughly revised, has given thousands of clinicians, students, and researchers a state-of-the-art understanding of the human frontal lobes--the large brain region that plays a critical role in behavior, cognition, health, and disease. Leading authorities from multiple disciplines address the anatomy and chemistry of the frontal cortex, neuropsychological assessments of capabilities unique to the frontal lobes, the nature of (and possible treatment avenues for) frontotemporal dementia and related conditions, and implications for understanding and treating neuropsychiatric disorders, such as schizophrenia, mania, and depression. Illustrations include eight pages in full color"--

Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurodevelopmental Disorders by Bin Chen,Kenneth Y. Kwan Book Summary:

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development

Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurodevelopmental Disorders by Randi Jenssen Hagerman Book Summary:

Neurodevelopmental Disorders: Diagnosis and Treatment summarizes a vast body of literature concerning diagnosis and treatment for a variety of neurodevelopmental disorders, including both common and rare conditions. Throughout the book, Dr. Hagerman synthesizes treatment information for many disciplines that work together to provide multi-modality intervention. Psychopharmacological information and recommendations as well as the latest knowledge regarding genetic and diagnostic aspects of each disorder are explained in detail. And all chapters have one or more case studies to model the treatment recommendations, which are enhanced by extensive appendices reviewing educational programs, computer software, and supplementary reading. In addition, a detailed resource list of organizations, educational materials, and internet connections accompanies each chapter. This book not only integrates but also advances our knowledge of treatment, which is of prime importance for clinicians, therapists, educators, and parents.

Neural and Synaptic Defects in Autism Spectrum Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neural and Synaptic Defects in Autism Spectrum Disorders by Hansen Wang,Laurie C. Doering Book Summary:

Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.

Translational Neuroscience

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Translational Neuroscience by James E. Barrett,Joseph T. Coyle,Michael Williams Book Summary:

Translational neuroscience is at the heart of clinical advancement in the fields of psychiatry, neurology and neurodevelopmental disorders. Written and edited by leading scientists and clinicians, this is a comprehensive and authoritative analysis of this emerging strategy for developing more effective treatments for brain disorders. Introductory chapters bring together perspectives from both academia and industry, while subsequent sections focus on disease groups, including bipolar disorder and depression, attention deficit hyperactivity disorder, substance abuse, autism, Alzheimer's disease, pain, epilepsy, Parkinson's disease and multiple sclerosis. Each section includes topical introductory and summary chapters, providing an overview and synthesis of the field. Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders is an important text for clinicians, scientists and students in academic settings, government agencies and industry, as well as those working in the fields of public health and the behavioural sciences.

Handbook of Schizophrenia Spectrum Disorders, Volume I

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Handbook of Schizophrenia Spectrum Disorders, Volume I by Michael S Ritsner Book Summary:

A few disorders have some of the same symptoms as schizophrenia including schizoaffective disorders, schizophreniform disorder, schizotypal and schizoid personality disorders, delusional disorder, and autism (schizophrenia spectrum disorders). Since the 2000 there has been significant progress in our understanding of the early presentations, assessment, suspected neuropathology, and treatment of these disorders. Recent technological breakthroughs in basic sciences hold promise for advancing our understanding of the pathophysiology of schizophrenia spectrum disorders. This collective monograph reviewers recent researches regarding the origins, onset, course, and outcome of schizophrenia spectrum disorders. In particular, this book will be illustrate new developments in terms of conceptual models, and research methodology, genetics and genomics, brain imaging and neurochemical studies, neurophysiology and information processing in schizophrenia spectrum disorders patients. Also will be highlighted new developments in our understanding of the childhood psychosis, prodromal and first-episode states, in treatment and rehabilitation. Thus, the purpose of this book is to provide up-to-date overview of the rapid advances made in the clinical and basic science studies supporting our understanding of the relationship between cerebral processes and clinical, cognitive and other presentations of the schizophrenia spectrum disorders. In addition, this book aims to monitor important research developments, which may be relevant to treatment, and rehabilitation of patients.

ADHD

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ADHD by Jill M. Norvilitis Book Summary:

With many children and adults affected by Attention Deficit Hyperactivity Disorder, researchers strive to improve our understanding of the causes, consequences, and treatment of the disorder. This volume examines some of the broad arrays of research in the field of ADHD, from etiology to cutting-edge interventions. The 16 chapters explore topics ranging from comorbidity to advances in the search for biomarkers; to executive, cognitive, and social functioning; to the use of new and alternative therapies. Both the professional and the casual reader alike will find something of interest, whether learning about ADHD for the first time or looking for inspiration for new research questions or potential interventions.

The Neurobiology of Schizophrenia

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

The Neurobiology of Schizophrenia by Ted Abel Book Summary:

"The Neurobiology of Schizophrenia "begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophreniaDiscusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levelsEdited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevanceElucidates connections between the various systems depicted, when possible

The SAGE Handbook of Developmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

The SAGE Handbook of Developmental Disorders by Patricia Howlin,Tony Charman,Mohammad Ghaziuddin Book Summary:

Over the last four decades, breakthroughs in genetic knowledge, together with the emergence of disciplines devoted to the scientific study of developmental disorders have resulted in much greater awareness of the many different behavioural and genetic phenotypes involved. It is now evident that not only do different disorders have different causes and different manifestations, but different neurological and biochemical bases, different responses to intervention, and different life courses. Reflecting the enormous changes that have taken place in our knowledge and understanding of developmental disorders, this groundbreaking international volume brings this vast and complex field together for the first time. The Editors have collected together the world's leading academic scholars and clinicians, to explore how current research across a range of different disciplines can inform clinical practice and help to improve the lives of individuals and their families.

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders by Lindsay M. Oberman,Peter G. Enticott Book Summary:

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback. Provides an overview of neuromodulatory devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents Gives evidence-based recommendations for non-drug interventions that may be effective for treatment options Discusses different neuromodulatory treatment options, including TMS, tDCS, DBS, chronotherapy and neurofeedback

Antipsychotics: Advances in Research and Application: 2011 Edition

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Antipsychotics: Advances in Research and Application: 2011 Edition by N.A Book Summary:

Antipsychotics: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Antipsychotics in a compact format. The editors have built Antipsychotics: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antipsychotics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antipsychotics: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS)

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The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS) by Flora Tassone,Elizabeth M. Berry-Kravis Book Summary:

In Fragile X-Associated Tremor Ataxia Syndrome (FXTAS), the editors present information on all aspects of FXTAS, including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms. Genetic counseling issues are also discussed. The book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments.

Autism Spectrum Disorder

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Autism Spectrum Disorder by Michael Fitzgerald Book Summary:

This book starts with a new sub category of Autism Criminal Autistic Psychopathy and school shootings. It focuses on a number of interventions, including speech and language pathology, speech and language assessment instruments, occupational therapy, improving functional language development in autism with natural gestures, communication boards etc as well as helping people with autism using the pictorial support, training of concepts of significant others, theory of mind, social concepts and a conceptual model for empowering families of children with autism cross culturally. It also examines the issue of hyperandrogenism and evidence-based treatments of autism. In terms of assessment, it focuses on psychological and biological assessment including neurotransmitters systems, structural and functional brain imaging, coping strategies of parents, examines the intertwining of language impairment, specific language impairment and ASD, as well as implicit and spontaneous Theory of Mind reading in ASD. In terms of aetiology, it focuses on genetic factors, epigenetics, synaptic vesicles, toxicity during neurodevelopment, immune system and sex differences. It also examines the link between social cognitive anatomical and neurophysiologic biomarkers and candidate genes. This book will be relevant to all mental health professionals because autism occurs in all the different areas of psychiatry and professionals who will find it helpful will be psychiatrists, psychologists, social workers, nurses, teachers and all those working with persons with Autism including parents who nowadays are interested in knowing more and more, at a detailed level about their children or adults with autism.

Sleep and ADHD

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Sleep and ADHD by Harriet Hiscock,Emma Sciberras Book Summary:

Sleep and ADHD begins with an overview of sleep (normal sleep, sleep cues, developmental phases, etc.) and continues with the epidemiology of ADHD and sleep problems, including medical issues (e.g. sleep apnea), parasomnias, behavioral insomnias (i.e. limit setting, sleep onset association disorders, circadian rhythm disorders and anxiety-related insomnia). It then covers the etiology of sleep problems, including the role of sleep hygiene and habits, the developing child, and the role of stimulants and medications used in the management of ADHD sleep problems. As the first book of its kind, users will find this reference an invaluable addition to the literature on ADHD. Covers both the pharmacological and non-pharmacological management of sleep problems Addresses sleep issues in younger children, but also addresses adolescents and adults Discusses the impact of sleep problems on the family as well as the child with ADHD Reviews the evidence around the neurobiology of sleep and systems regulating sleep in ADHD

Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurodevelopmental Disorders by Emanuel DiCicco-Bloom,James H. Millonig Book Summary:

This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management by M. Mohamed Essa,M. Walid Qoronfleh Book Summary:

The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.

Neuropsychiatric Disorders and Epigenetics

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neuropsychiatric Disorders and Epigenetics by Dag Yasui,Dennis R. Grayson,Jacob Peedicayil Book Summary:

"Neurobehavioral Disorders and Epigenetics" is a comprehensive reference for the epigenetic basis of most common neurobehavioral disorders. The volume is organized into 22 chapters representing individual neurological disorders, from Addiction to Stress. The epigenetic aspects of each disorder are addressed by at least two scientists with expertise in that research area. Particular emphasis is placed by each contributing author on potential epigenetic interventions. In an effort to cover a broad range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA, author contributions were selected accordingly. In addition the effects of environmental stimuli on epigenetic states is addressed in some chapters based on relevance to disease induction. Recent discoveries in epigenetic research enabled by advances in genomic technologies, have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders. Clearly neurobehavioral disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with high costs to society. Thus, these collected works will define epigenetics as a key player in neurobehavioral disorders, highlight the full spectrum of epigenetic mechanisms underlying such disorders and introduce the vast range of epigenetic therapies under development. Relates the effects of environmental stimuli on epigenetic states to neurological disease inductionAnalysis of the epigenetic basis for common neuropsychiatric disorders and how it guides treatment, providing insight and perspective to both clinicians and basic scientistsExtensive use of diagrams, illustrations and tables, and graphical abstracts for each subsection permits rapid review

Trauma, Autism, and Neurodevelopmental Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Trauma, Autism, and Neurodevelopmental Disorders by Jason M. Fogler,Randall A. Phelps Book Summary:

This book examines the diagnostic overlap and frequent confusion between the newly named DSM-5 diagnostic categories of neurodevelopmental disorders (NDDs), which include autism spectrum disorder (ASD), and trauma and stressor related disorders (TSRDs). These conditions are similar in that a) children with developmental disorders are particularly vulnerable to traumatic events and b) all have pervasive effects on the brain and development. Chapters provide a wealth of effective clinical, family, and school-based interventions, developed from established studies and important new findings. In addition, chapters use illustrative case studies to survey assessment challenges in today’s healthcare climate and consider alternative routes for improving correct diagnoses, identifying appropriate interventions, and referring proper targeted, evidence-based treatment and services. The book concludes with the editors’ recommendations for needs-based service access, including a more widespread use and acceptance of the Research Domain Criteria (RDoC) and the International Classification of Functioning, Disability, and Health (ICF) framework. Topics featured in this book include: The neurobiological contributors to posttraumatic stress disorder (PTSD). Fetal alcohol spectrum disorders (FASDs) and its diagnosis in children with a history of trauma. Interventions for trauma and stressor-related disorders in preschool-aged children. Reactive attachment disorder (RAD) and autism spectrum disorder (ASD) diagnosis and care in a cultural context. Special population consideration in ASD identification and treatment. Challenges associated with the transition to adulthood. Trauma and neurodevelopmental disorders from a public health perspective. Trauma, Autism, and Neurodevelopmental Disorders is a must-have resource for researchers, clinicians and related professionals, and graduate students in developmental psychology, child and adolescent psychiatry, public health, social work, pediatrics, and special education.

Treatment Resistance in Psychiatry

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Treatment Resistance in Psychiatry by Yong-Ku Kim Book Summary:

This book reviews all the important aspects of treatment-resistant psychiatric disorders, covering issues such as definitions, clinical aspects, neurobiological correlates, treatment options, and predictors of treatment response. The book is divided into three sections, the first of which examines the most recent thinking on treatment resistance in psychiatry, including definition and epidemiology, paradigm shift in the study of the subjects, individual susceptibility and resilience, abnormal structural or functional connectivity, and insights from animal models. The second section then discusses treatment resistance in each of the major psychiatric disorders, with particular focus on the responsible clinical and biological factors and the available management strategies. Finally, more detailed information is presented on diverse pharmacological and non-pharmacological therapeutic interventions. The book, written by leading experts from across the world, will be of value to all who seek a better understanding of the clinical-neurobiological underpinnings and the development of management for treatment resistance in psychiatric disorders.

The Prescriber's Guide, Antidepressants

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

The Prescriber's Guide, Antidepressants by Stephen M. Stahl Book Summary:

This is a spin-off from Stephen M. Stahl's new, completely revised and updated version of his much-acclaimed Prescriber's Guide, covering drugs to treat depression.

Neurodevelopmental Disabilities

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurodevelopmental Disabilities by Michael Shevell Book Summary:

"Neurodevelopmental disabilities are a common problem in child health. This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment. It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes are also addressed in a detailed way. The book has wide appeal to those in paediatrics, developmental paediatrics, child neurology, and paediatric rehabilitation. Its geographic appeal includes both developed and developing nations as some chapters are devoted to the particular issues faced in underdeveloped countries. The book's focus on both clinical and scientific aspects is invaluable in this field. It also provides extensive information in a single source relating to often-overlooked areas such as medical management, rehabilitation, public policy, and ethics."--Publisher's website.

Child and Adolescent Mental Health

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Child and Adolescent Mental Health by Martin Henrik Maurer Book Summary:

In the present volume, we collected state-of-the-art chapters on diagnosis, treatment, and social implications. The first section describes diagnostic processes. It describes a reevaluation of projective techniques, a new clinical tool in psychotraumatology, the foundations of the framing technique, and an overview on integrative approaches. The second section focuses on new developments in the field with special emphasis on culture-specific contexts. From parenting of adolescents in India to the influence of poverty on mental health issues in Mexico, as well as the use of marijuana and Internet addiction, some of the most important fields are highlighted. The third section concentrates on therapy. It shows how to react to bullying and reviews the use of antidepressants in children and adolescents.

Neurological Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neurological Disorders by World Health Organization Book Summary:

Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.

Movement Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Movement Disorders by Mark S. LeDoux Book Summary:

The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. * Provides a single comprehensive resource on animal models of movement disorders that academic clinicians, translational researchers, and basic neuroscientists can refer to * Includes contributions by expert movement disorder clinicians and top-level researchers in the field * Features a DVD containing over 170 video clips of human movement disorders and the corresponding animal models

Neurobiology of Brain Disorders

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Neurobiology of Brain Disorders by Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland Book Summary:

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Child and Adolescent Psychiatry

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Child and Adolescent Psychiatry by Savita Malhotra,Paramala Santosh Book Summary:

This is a comprehensive volume on issues and concerns relating to child and adolescent mental health in Asia, which includes contributions from experts in child psychiatry from Asia and other parts of the world. The chapters provide accurate and detailed accounts of the current state of knowledge integrating research approaches and findings from clinical studies. Each chapter discusses existing information, emphasizes areas of growth and provides fresh insights on a particular topic especially as these might relate to Asian populations. The book integrates various clinical and scientific perspectives on psychiatric disorders in children and adolescents with a focus on Asia. The various sections deal with important topics in child and adolescent psychiatry: the current understanding of mental disorders and the ways in which possible influences might work in the development of psychopathology; substance use disorders, their neurobiological correlates and implications for the developing brain; early environmental influences in the psychopathology of psychiatric disorders in children; issues of parenting, child rearing and cultural practices in Asia, which influence personality development and adaptation; life-long impact of early parental loss; early diagnosis and intervention in recognizing and treating psychopathology; psychopharmacology of neurodevelopmental disorders in children; non-pharmacological treatments for children; mental health gap, and telepsychiatry as an innovative model to provide services for children; and a pressing need for a comprehensive child mental health policy across nations.

Clinical Staging in Psychiatry

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Clinical Staging in Psychiatry by Patrick D. McGorry,Ian B. Hickie Book Summary:

Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.

Neurology of the Newborn

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Neurology of the Newborn by Joseph J. Volpe Book Summary:

Download or read Neurology of the Newborn book by clicking button below to visit the book download website. There are multiple format available for you to choose (Pdf, ePub, Doc).

The Neuroscience of Hallucinations

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The Neuroscience of Hallucinations by Renaud Jardri,Arnaud Cachia,Pierre Thomas,Delphine Pins Book Summary:

Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: Hallucinations in the healthy individual. A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling. Molecular mechanisms of hallucinogenic drugs. Structural and functional variations in the hallucinatory brain in schizophrenia. The neurodevelopment of hallucinations. Innovations in brain stimulation techniques and imaging-guided therapy. Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.

Frontiers in Autism Research

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Frontiers in Autism Research by Valerie W. Hu Book Summary:

This unique book focuses on the emerging and expanding areas of research on autism spectrum disorders (ASD). These areas include investigations of genome-wide genetics and epigenetic contributions, metabolic and immune dysfunction, gene-environment interactions, as well as the role of alternative splicing, RNA editing, and noncoding RNAs in gene regulation. Advances in targeted or personalized therapies and alternative interventions, such as music and art therapy, are also presented. In addition, current research on issues involving adults with ASD, a population that has been sorely neglected in the field of autism, is discussed. Within each chapter, experts will review the current status of autism research in his/her field as well as provide a look at the direction where the field will (or should) be headed over the next five years and discuss the translational (practical) outcomes that are anticipated through this research. Some chapters are devoted to the development of molecular or genetic diagnostics for ASD, and novel therapeutic options that are emerging based upon new biological findings on specific genes, pathways, and metabolic functions disrupted in ASD. These unique features are designed to provide "food for thought" for future studies on autism. Hence, this book will be of value not only to established investigators and students conducting research on autism, but also to the general population especially families of individuals affected by ASDs.

Autism 360°

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Autism 360° by Undurti N. Das,Neophytos Papaneophytou,Tatyana El-Kour Book Summary:

Autism 360 uses a hybrid and transdisciplinary methodology to identify mechanisms on how autism is prevented, diagnosed, treated and managed within personal and social constructs around the world. Adopting a lifespan approach, the book discusses lifestyle challenges and emphasizes issues relating to neurodiversity, individuality, best practices, and support of both people on the spectrum and their families. This book will help change population and individual attitudes and behaviors regarding autism. Its ultimate goal is to empower readers to become both agents of change and an integral part of the solution. Covers topics from the prevention and treatment of autism and how to live with it Adopts an integrated methods approach Features field experiences Provides valuable syntheses of scattered material Compares cross-cultural learnings Discusses the education and employment of those with autism

Neuropsychopharmacology

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Neuropsychopharmacology by Kenneth L. Davis,American College of Neuropsychopharmacology Book Summary:

Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Handbook of Life Course Health Development

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Handbook of Life Course Health Development by Neal Halfon,Christopher B. Forrest,Richard M. Lerner,Elaine M. Faustman Book Summary:

This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

The Molecular Basis of Autism

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

The Molecular Basis of Autism by S. Hossein Fatemi Book Summary:

This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.

Textbook of Autism Spectrum Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Textbook of Autism Spectrum Disorders by Eric Hollander,Alex Kolevzon,Joseph T. Coyle Book Summary:

More patients are diagnosed with autism, and at earlier ages, than ever before, and these patients and their families receive services in increasingly diverse settings. Destined to become a classic, this is the volume for which patients, families, and clinicians have been waiting.

Autism Spectrum Disorders

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Autism Spectrum Disorders by Eric Hollander, M.D.,Randi Hagerman, M.D.,Deborah Fein, Ph.D. Book Summary:

In DSM-5, published in 2013, the classification of autism spectrum disorder (ASD) was created, subsuming several diagnoses and representing a significant evolution from its first appearance in the DSM-III three decades earlier. Autism Spectrum Disorders reflects this evolution, offering clinicians and families a succinct, definitive, and up-to-date guide to current research in the field and its impact on assessment and treatment. The book begins with the epidemiology of ASDs, which have increased in prevalence, and explores genetic heritability and environmental risk factors. It then explains the roles of the psychiatrist, neurologist and pediatrician in assessing the patient, examines assessment tools and processes, and describes the latest advances in a variety of treatments and interventions. The text's focus is on educating and empowering families and health care providers to determine whether appropriate genetic testing and counseling have been undertaken, whether the individual has had the relevant assessment, and whether skilled behavioral treatment and additional medical assessment or treatment are required. Specifically, the text: * Reviews existing prevalence estimates for ASDs since 2000 and discusses methodological factors impacting the estimation of prevalence and the interpretation of changes in prevalence estimates over time.* Evaluates genomic and epigenomic research over the last decade in the context of translating findings to practice, in terms of testing (e.g., copy number variants and whole-exome sequencing) and counseling.* Examines the role of environmental toxicity in immune dysregulation, which has now been noted among individuals with ASD and their family members by numerous studies. * Reviews medical and cognitive assessments that may be needed.* Reviews targeted treatments that have the potential to reverse neurobiological abnormalities in ASD* Reviews behavioral treatments that are effective in promoting development and improving behavior.* Describes the Developmental, Individual Difference, Relationship-based (DIR) model, a comprehensive developmental theory with relevance across the lifespan, which targets the core deficits of ASD identified in DSM-5.* Provides an overview of school-based interventions for students with autism, exploring the rationale for conducting school-based research and examining existing teacher-, paraprofessional-, and peer-mediated interventions school-based interventions.* Explores other approaches to ASDs, such as complementary and integrative approaches and non-invasive brain stimulation technologies, including transcranial magnetic stimulation. The push for early screening is resulting in earlier diagnosis of ASDs and the provision of evidence-based interventions that have a positive impact on outcomes. Autism Spectrum Disorders provides a bench-to-bedside guide that is essential reading for health care providers and families facing the challenges inherent in these complex disorders.

Schizophrenia Treatment

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Schizophrenia Treatment by Yu-Chih Shen Book Summary:

Schizophrenia treatment has many facets. This book begins with the glutamatergic and GABAergic hypofunctioning contribute to the schizophrenic symptoms and their current targeted therapeutics. The genetic, epigenetic, and immune etiologies of schizophrenia and their potential targeted therapeutics as approached in this book are interesting. Understanding cognitive biases and delusional circuits in schizophrenia is important; several behavioral cognitive therapies working on the reduction and avoidance of these cognitive biases are demonstrating their effectiveness. Advances in schizophrenia treatment followed, including transcranial magnetic stimulation and special sport program, are presented at the book's end.

Advancements of Mass Spectrometry in Biomedical Research

Treatment Of Neurodevelopmental Disorders Targeting Neurobiological Mechanisms [Pdf/ePub] eBook

Advancements of Mass Spectrometry in Biomedical Research by Alisa G. Woods,Costel C. Darie Book Summary:

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.