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Top Drugs History Pharmacology Syntheses

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Top Drugs

Top Drugs History Pharmacology Syntheses [Pdf/ePub] eBook

Top Drugs by Jie Jack Li Book Summary:

"A thorough examination of the chemistry and history of ten prominent prescription drugs"--

An Introduction to Medicinal Chemistry

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An Introduction to Medicinal Chemistry by Graham Patrick Book Summary:

For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market?An Introduction to Medicinal Chemistry, sixthedition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Inaddition to covering the key principles of drug design and drug action, the text also discusses important current topics in medicinal chemistry. The subject is brought to life throughout by engaging case studies highlighting particular classes of drugs, and the stories behind their discovery and development.

Blockbuster Drugs

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Blockbuster Drugs by Jie Jack Li Book Summary:

"This book uses the cases of several landmark drugs to discuss the history of the pharmaceutical industry, and discusses what could be next"--Provided by publisher.

Synthesis of Essential Drugs

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Synthesis of Essential Drugs by Ruben Vardanyan,Victor Hruby Book Summary:

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

The Chemistry of Mind-altering Drugs

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The Chemistry of Mind-altering Drugs by Daniel M. Perrine Book Summary:

This fascinating book presents a scientifically objective, and thoroughly documented exposition of the pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to Zopiclone. It also features first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used, and discusses historical allusions to many literary and scientific figures who used or wrote of mind-altering drugs, including Freud, Dickens, Yeats, and Huxley. Intended for a wide audience of general readers seeking unbiased information, the book gives an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. Written by an experienced chemist, the book nevertheless keeps technical information to a minimum.

Contemporary Drug Synthesis

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Contemporary Drug Synthesis by Jie Jack Li,Douglas S. Johnson,Drago R. Sliskovic,Bruce D. Roth Book Summary:

An integrated and insightful look at successful drug synthesis intoday's drug discovery market The pharmaceutical industry is unquestionably vibrant today,with drug synthesis making a vital contribution. Whether in theearly developmental stages of identifying and optimizing a lead, orthe latter stages of process development and cost-effectivescale-up, the ability to design elegant and economical syntheticroutes is often a major factor in the eventual viability andcommercial success of a drug. Contemporary Drug Synthesis examines how leadingresearchers and manufacturers have integrated chemistry, biology,pharmacokinetics, and a host of other disciplines in the creationand development of leading drugs. Authored by four of the pharmaceutical industry's most respectedscientists, this timely volume: Focuses on the processes that resulted in high-profile drugsincluding Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, andover a dozen others Provides an in-depth introduction to each drug, followed by adetailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarityand ease of use Process chemists provide an essential bridge between chemistry andthe marketplace, creating scientifically practical drug processeswhile never losing sight of the commercial viability of thoseprocesses. Contemporary Drug Synthesis meets the needs of agrowing community of researchers in pharmaceutical research anddevelopment, and is both a useful guide for practicingpharmaceutical scientists and an excellent text for medicinal andorganic chemistry students.

The Organic Chemistry of Drug Synthesis

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The Organic Chemistry of Drug Synthesis by Daniel Lednicer Book Summary:

The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

Contemporary Drug Synthesis

Top Drugs History Pharmacology Syntheses [Pdf/ePub] eBook

Contemporary Drug Synthesis by Jie Jack Li,Douglas S. Johnson,Drago R. Sliskovic,Bruce D. Roth Book Summary:

An integrated and insightful look at successful drug synthesis intoday's drug discovery market The pharmaceutical industry is unquestionably vibrant today,with drug synthesis making a vital contribution. Whether in theearly developmental stages of identifying and optimizing a lead, orthe latter stages of process development and cost-effectivescale-up, the ability to design elegant and economical syntheticroutes is often a major factor in the eventual viability andcommercial success of a drug. Contemporary Drug Synthesis examines how leadingresearchers and manufacturers have integrated chemistry, biology,pharmacokinetics, and a host of other disciplines in the creationand development of leading drugs. Authored by four of the pharmaceutical industry's most respectedscientists, this timely volume: Focuses on the processes that resulted in high-profile drugsincluding Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, andover a dozen others Provides an in-depth introduction to each drug, followed by adetailed account of its synthesis Organizes the drugs into fourteen therapeutic areas for clarityand ease of use Process chemists provide an essential bridge between chemistry andthe marketplace, creating scientifically practical drug processeswhile never losing sight of the commercial viability of thoseprocesses. Contemporary Drug Synthesis meets the needs of agrowing community of researchers in pharmaceutical research anddevelopment, and is both a useful guide for practicingpharmaceutical scientists and an excellent text for medicinal andorganic chemistry students.

The Top 100 Drugs

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The Top 100 Drugs by Andrew Hitchings,Dagan Lonsdale,Daniel Burrage,Emma Baker Book Summary:

Now in its second edition, this highly successful guide to safe prescribing of the most common classes of drugs is your starting point for safe and effective practice. The first edition was a direct response to requests from students for a compendium of the 100 most important drugs in the NHS. Research led by Professor Emma Baker identified the ‘top 100 drugs’ by their importance and prescribing frequency. The top 100 drugs and the five most important intravenous fluids are presented using a clear, consistent layout across double-page spreads. Drugs are arranged alphabetically and also listed by organ system and clinical indication, providing multiple pathways into the information. Clinical pharmacology is discussed under the headings: common indications; mechanisms of action; important adverse effects; warnings; and important interactions. Practical prescribing is discussed under the headings: prescription; administration; communication; monitoring; and cost. A clinical tip is presented for every drug. Single-best-answer questions are provided for self-assessment and to show how information from several drugs may be integrated.

Peptides

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Peptides by Bernd Gutte Book Summary:

In recent years, research has shown the importance of peptides in neuroscience, immunology, and cell biology. Active research programs worldwide are now engaged in developing peptide-based drugs and vaccines using modification of natural peptides and proteins, design of artificial peptides and peptide mimetics, and screening of peptide and phage libraries. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry. Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic polypeptides. The history of peptide chemistry Amide formation, deprotection, and disulfide formation in peptide synthesis Solid-phase peptide synthesis a-helix formation by peptides in water Stability and dynamics of peptide conformation An overview of structure-function studies of peptide hormones Neuropeptides:peptide and nonpeptide analogs Reversible inhibitors of serine proteinases Design of polypeptides Current capabilities and future possibilities of soluble chemical combinatorial libraries Epitope mapping with peptides Synthesis and applications of branched peptides in immunological methods and vaccines

Introduction to Pharmacology, Third Edition

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Introduction to Pharmacology, Third Edition by Mannfred A. Hollinger Book Summary:

Advances in pharmacogenomics and proteomics, along with the introduction of recombinant DNA technology, have expanded the applications of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the development and delivery of novel drugs. Therefore, students in a variety of life sciences now require grounding in pharmacology. Adding much new material, Introduction to Pharmacology, Third Edition familiarizes students with the curative action of specific drugs, along with current research and the multifaceted role of pharmacology in society. New to the third edition— · Chapters on smooth muscle pharmacology covering gastrointestinal and pulmonary pharmacology · Pharmacology advances at the molecular level · The historical background of the Watson Crick model of DNA · Cutting edge topics such as RNA interference and dopamine signaling The text begins with a discussion on the absorption, distribution, metabolism, and elimination of drugs. Much emphasis is placed on pharmacokinetic aspects: how drugs produce an effect and the quantification of these effects for comparative purposes. Also the text describes substance abuse pharmacology and the evolution of drug laws. Several chapters deal with the development of drugs and challenges faced in drug discovery. Identifying both the therapeutic and toxicological aspects of drug use, Introduction to Pharmacology employs contemporary examples to help students become familiar with drug development and treatment, as well as possible adverse affects, and the impact of drug research and use on society today and into the future.

The Art of Drug Synthesis

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The Art of Drug Synthesis by Douglas S. Johnson,Jie Jack Li Book Summary:

The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Privileged Scaffolds in Medicinal Chemistry

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Privileged Scaffolds in Medicinal Chemistry by Stefan Bräse Book Summary:

One strategy to expedite the discovery of new drugs, a process that is somewhat slow and serendipitous, is the identification and use of privileged scaffolds. This book covers the history of the discovery and use of privileged scaffolds and addresses the various classes of these important molecular fragments. The first of the benzodiazepines, a class of drugs that is powerful for treating anxiety, may not have been discovered had it not been for a chance experiment on the contents of a discarded flask found during a lab clean-up. Some years later, scientists discovered that benzodiazepine derivatives were also effective in treating other diseases. This class of molecules was the first to be described as privileged in the sense that it is especially effective at altering the course of disease. Other privileged molecular structures have since been discovered, and since these compounds are so effective at interacting with numerous classes of proteins, they may be an effective starting point to look for new drugs against the supposedly "undruggable" proteins. Following introductory chapters presenting an overview, a historical perspective and the theoretical background and findings, main chapters describe the structure of privileged structures in turn and discuss major drug classes associated with them and their syntheses. This book provides comprehensive coverage of the subject through chapters contributed by expert authors from both academia and industry and will be an excellent reference source for medicinal chemists of a range of disciplines and experiences.

Top Drugs: Top Synthetic Routes

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Top Drugs: Top Synthetic Routes by John Saunders Book Summary:

This book will allow students to see how the organic chemistry taught in undergraduate courses is applied by medicinal chemists in industry. Many of today's best selling drugs are first made in the chemical laboratory on a very small scale many years before they enter the market place. During the intervening period, organic chemists investigate alternative methods both to improve the overall yield of the process and to ensure that it operates safely on a manufacturing scale. This book describes briefly how each drug works and then reviews the most efficient routes to their synthesis.

Our Love Affair with Drugs

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Our Love Affair with Drugs by Jerrold Winter Book Summary:

Prescription, illicit, and recreational drugs touch all of our lives yet a basic understanding of these chemicals is largely absent among Americans. Jerrold Winter offers a comprehensive account of psychoactive drugs, chemicals which influence our brains in myriad ways. Manifestations of their influence on the brain are quite varied. There may be the comfort provided by opioids to those who are dying or in pain or, in everyday life, the surge of contentment for the users of caffeine, nicotine, heroin, alcohol, or marijuana upon the taking of their drug of choice. Turning to the more exotic, a drug such as LSD may alter the way the world looks to us; it may even inspire thoughts of God. Adding to the purely scientific questions which confront us are the ways in which our society chooses to respond to the presence of psychoactive drugs. Should they be banned and their users sent to prison, tolerated as a reflection of man's eternal search for an escape from anxiety, pain, and the monotony of daily life, or celebrated as therapeutically useful agents? Our Love Affair with Drugs is written for experts and novices alike. There are stories of, for example, how Timothy Leary caused the repeal of the Marijuana Tax Act of 1937. Readers will learn of the transformation by Sir Charles Locock of a drug intended to dampen female sexual activity into the first effective drug for the treatment of the ancient disease of epilepsy. Alexander Shulgin's love of psychoactive drugs and his unconventional research practices illuminate the story of methylenedioxymethamphetamine, a.k.a. Ecstasy, a drug now likely to find value in treating veterans and others suffering post-traumatic distress disorder. Winter links the excitement of drug discovery with the very practical matter of balancing the benefits and risks of these drugs.

The Practice of Medicinal Chemistry

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The Practice of Medicinal Chemistry by Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan Book Summary:

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com

Triumph of the Heart

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Triumph of the Heart by Jie Jack Li Book Summary:

Over 25 million people in the U.S. alone have benefited from statins--such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines--in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, Triumph of the Heart offers a compelling view of one of the most important drug discoveries of our time.

Modern Drug Synthesis

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Modern Drug Synthesis by Jie Jack Li,Douglas S. Johnson Book Summary:

Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of twenty different drug molecules.

Medical Monopoly

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Medical Monopoly by Joseph M. Gabriel Book Summary:

Drawing on a wealth of previously unused archival material, this title combines legal, medical and business history to offer a sweeping new interpretation of the origins of the complex and often troubling relationship between the pharmaceutical industry and medical practice today.

Drug Stereochemistry

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Drug Stereochemistry by Krzysztof Jozwiak,W. J. Lough,Irving W. Wainer Book Summary:

Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology. Topics include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery How stereochemistry impacts decisions made in the absorption, distribution, metabolism, excretion, and toxicity (ADMET) stages of drug discovery Pharmacokinetics and pharmacodynamics and the issues faced during the final stages of the drug development process The impact of the International Conference on Harmonisation (ICH) on the use of single isomer drugs Chiral switches The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs Patent issues surrounding chiral switches and the marketing of single enantiomer switches The book provides a solid background on stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. It is a one-stop reference for pharmaceutical scientists and chemists working with chiral drug molecules.

Drugs

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Drugs by Les Iversen Book Summary:

The twentieth century saw a remarkable upsurge of research on drugs, with major advances in the treatment of bacterial and viral infections, heart disease, stomach ulcers, cancer, and metal illnesses. These, along with the introduction of the oral contraceptive, have altered all of our lives. There has also been an increase in the recreational use and abuse of drugs in the Western world. This Very Short Introduction, in its second edition, gives a non-technical account of how drugs work in the body. Reviewing both legal (alcohol, nicotine, and caffeine) and illegal drugs, Les Iversen disscusses why some are addictive, and whether drug laws need reform. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Introduction to Natural Products Chemistry

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Introduction to Natural Products Chemistry by Rensheng Xu,Yang Ye,Weimin Zhao Book Summary:

Natural products chemistry-the chemistry of metabolite products of plants, animals and microorganisms-is involved in the investigation of biological phenomena ranging from drug mechanisms to gametophytes and receptors and drug metabolism in the human body to protein and enzyme chemistry. Introduction to Natural Products Chemistry has collected the

The Drug Book

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The Drug Book by Michael C. Gerald Book Summary:

Covering everything from ancient herbs to cutting-edge chemicals, examines the most important moments in the development of pharmaceuticals and includes discussions of vaccines, homeopathic cures, and controversial treatments.

Amphetamine Syntheses

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Amphetamine Syntheses by Otto Snow Book Summary:

Download or read Amphetamine Syntheses book by clicking button below to visit the book download website. There are multiple format available for you to choose (Pdf, ePub, Doc).

The Evolution of Drug Discovery

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The Evolution of Drug Discovery by Enrique Ravina Book Summary:

Based on his profound knowledge of past and present paradigms in the development of medicines, the author takes the reader from the very beginnings of pharmacology to the multibillion-dollar business it represents today. Recounting the often spectacular successes and failures of innovative drugs as well as the people who discovered them, he brings abstract science to life in anecdotal form. The book is beautifully illustrated, containing historical photographs of drugs and their discoverers, and abounds with references to the primary literature, listing seminal publications alongside more modern reviews for readers seeking further details. For anyone with a more than superficial interest in the science of drugs: instructive and enjoyable for a broad audience of students, instructors and professionals in pharmacy, the pharmaceutical chemistry and related fields.

Pharmaceutical Innovation After World War II: From Rational Drug Discovery to Biopharmaceuticals

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Pharmaceutical Innovation After World War II: From Rational Drug Discovery to Biopharmaceuticals by Apostolos Zarros,Tilli Tansey Book Summary:

Download or read Pharmaceutical Innovation After World War II: From Rational Drug Discovery to Biopharmaceuticals book by clicking button below to visit the book download website. There are multiple format available for you to choose (Pdf, ePub, Doc).

Clinical Pharmacology

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Clinical Pharmacology by Morris J. Brown,Pankaj Sharma,Peter N. Bennett Book Summary:

A thorough knowledge of pharmacological and therapeutic principles is vital if drugs are to be used safely and effectively for increasingly informed patients. Those who clearly understand how drugs get into the body, how they produce their effects, what happens to them in the body, and how evidence of their therapeutic effect is assessed, will choose drugs more skilfully, and use them more safely and successfully than those who do not. Now in a fully revised 11th edition, Clinical Pharmacology is essential reading for undergraduate medical students, junior doctors and anyone concerned with evidence-based drug therapy. Introductory first three sections cover general principle of clinical pharmacology; five subsequent sections cover drug treatment of disease organised by body system. Retains approachable style set by the original author, Professor Laurence. Emphasis throughout is on evidence-based and safe drug prescribing. Indian Advisory Board will ensure content reflects the needs of the devloping world.

Aspirin

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Aspirin by Diarmuid Jeffreys Book Summary:

Throughout the world we pop more than 200 billion of these little white pills every year. Aspirin is effective not only against everyday ailments, such as headaches and fever, but also as a preventative treatment for heart attacks, strokes, and even some types of cancers. Add to this its beneficiary role in a host of other conditions from Alzheimer's to gum disease, and you have a medicine of unparalleled importance to humanity, not to mention big business. Yet until 1971 we did not even know how Aspirin worked. In this fascinating and informative book Diarmuid Jeffreys follows the surprising and dramatic story of the drug from its origins in ancient Egypt, through its industrial development at the end of the nineteenth century and its key role in the great flu pandemic of 1918 to its subsequent exploitation by the pharmaceutical conglomerates.

Clinical Pharmacology and Nursing

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Clinical Pharmacology and Nursing by Charold Lee Morris Baer,Bradley R. Williams Book Summary:

Includes software offering more than 1,300 multiple-choice questions and other activities complete with answers and rationales, nursing process step, client needs category, taxonomic level when applicable, chapter and unit tests, a comprehensive test, and a score report. Text has been updated to include all approved drugs. Contents include general pharmacology, the nursing process and pharmacotherapeutics, coverage of all drug classes, and data on hundreds of generic drugs. Charts, diagrams, and illustrations.

Essentials of Clinical Pharmacology in Nursing

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Essentials of Clinical Pharmacology in Nursing by Bradley R. Williams,Charold Lee Morris Baer Book Summary:

Concise presentation of basic pharmacologic information for the students. Units one and two address fundamentals of pharmacology and drug administration. Units three to 16 group drugs by therapeutic classification with each chapter covering pharmacokinetics, pharmacodynamics, pharmacotherapeutics, adverse drug reactions and nursing process steps in administering drugs. The disk contains questions and answers for self-study.

Oxford Textbook of Medicine

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Oxford Textbook of Medicine by D. A. Warrell,Timothy M. Cox,John D. Firth Book Summary:

Download or read Oxford Textbook of Medicine book by clicking button below to visit the book download website. There are multiple format available for you to choose (Pdf, ePub, Doc).

Laughing Gas, Viagra, and Lipitor

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Laughing Gas, Viagra, and Lipitor by Jie Jack Li Book Summary:

This is a book on the history of drug discovery that highlights the intellectual splendor of discoverers as well as the human frailty associated with them.

The Top 100 Drugs e-book

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The Top 100 Drugs e-book by Andrew Hitchings,Dagan Lonsdale,Daniel Burrage,Emma Baker Book Summary:

Prescribing for the first time is a nerve-wracking experience. Of all the tasks performed by new doctors, it is probably the one with greatest direct impact on the wellbeing of patients. Safe and effective practice rests on a good understanding of both clinical pharmacology and practical prescribing. Acquiring this is not easy, particularly when faced with reams of information about hundreds of unfamiliar drugs, often presented in a way that appears detached from clinical reality. This book is your starting point. It is a direct response to requests from students for a compendium of the 100 most important drugs in the NHS. Key information about the clinical pharmacology and practical prescribing of each drug is presented side-by-side, allowing you to direct your attention as appropriate for your stage of training. Drugs can be accessed alphabetically when you need quick information on the wards and by organ system or clinical indication when you are at your desk. Research led by Professor Emma Baker has identified the ‘top 100 drugs’ by their importance and prescribing frequency. She has shown that the list changes little over time, making it a stable resource upon which to base learning. The top 100 drugs and the five most important intravenous fluids are presented using a clear, consistent layout across double-page spreads. Drugs are arranged alphabetically and also listed by organ system and clinical indication, providing multiple pathways into the information. Clinical pharmacology is discussed under the headings: common indications; mechanisms of action; important adverse effects; warnings; and important interactions. Practical prescribing is discussed under the headings: prescription; administration; communication; monitoring; and cost. A clinical tip is presented for every drug. Single-best-answer questions are provided for self-assessment and to show how information from several drugs may be integrated.

Commonly Used Drugs

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Commonly Used Drugs by Rafik Karaman Book Summary:

Drugs (medicines) are considered either the primary therapy or an adjunct to another modality. Physicians of all specialties prescribe drugs on a daily basis, and therefore they need to understand the mode and action by which drugs exert their therapeutic effects. Written records of the use of natural products as medicinal agents date back thousands of years. However, it was not until the early 1800s that the active principles from plants were isolated. Since then thousands of drugs have been introduced to the drugs market. With advances in drug design, molecular biology and genetics, the rate of developing new potent drugs is accelerated. Due to the vast progress in drug development and discovery, medical and pharmacy students, doctors, nurses and pharmacists in training need to learn the principles of therapeutics in order to follow up with the frequent changes in the therapeutics and adapt to them. With contributions from some of my colleagues, this book provides a clear and concise overview of the most important commonly used drugs with emphasis on the pharmacology aspects necessary for a basic understanding of the subject. It reviews the concepts, clinical applications, dosage forms, bioavailability, pharmacokinetics and side effects of a large number of drugs used to alleviate pain, lower cholesterol levels, and treat bacterial infections, diabetes, osteoporosis, bleeding, psoriasis and multiple Sclerosis. This book, with over 750 references, is an excellent pharmacology text for the student who is looking to broaden his/her strengths prior to the exam. The beauty of this text is that it includes essential pharmacology concepts in a compact book that can be quickly referenced and read multiple times during the course of a student's studies. In addition, this guide assists scientists trained in molecular biology, medicinal chemistry and related fields who need to know the basic theories, principles and practical applications of pharmacology. With the addition of pharmacokinetics coverage, ways to improve the bioavailability of commonly used drugs and sections on therapeutics that will help readers identify with diseases and drug treatments, this book provides better preparation of researchers in the basics of pharmacology.

Pharmacology for the Primary Care Provider - E-Book

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Pharmacology for the Primary Care Provider - E-Book by Marilyn Winterton Edmunds,Maren Stewart Mayhew Book Summary:

Written by and for nurse practitioners, this practical textbook focuses on what primary care providers need to learn and practice drug therapy. With an overall emphasis on patient teaching and health promotion, you will learn how to provide effective patient teaching about medications and how to gain patient compliance. Drug coverage focuses on “key drugs rather than “prototype drugs, so you can find important information about the most commonly used drugs rather than the first drug in each class. You will also find discussions on the legal and professional issues unique to nurse practitioners and other primary care providers. The 3rd edition also features an expanded emphasis on established clinical practice guidelines and evidence-based practice, plus two new chapters that cover drugs for ADHD and drugs for dementia. UNIQUE! Written specifically for nurse practitioners with an overall emphasis on patient teaching and health promotion. UNIQUE! Covers specific topics such as prescriptive authority, role implementation, and writing prescriptions. Presents comprehensive coverage of the drugs most commonly prescribed in – and the issues most relevant to – primary care practice. UNIQUE! Identifies the Top 200 drugs in chapter openers with a special icon and covers them in-depth to familiarize you with the most important, need-to-know drug information. Uses a consistent heading scheme for each prototype drug discussion to make it easier to learn and understand key concepts. Includes an introductory chapter on “Design and Implementation of Patient Education that highlights content on patient teaching and compliance. Includes specific “Patient Education sections in each drug chapter. Provides extensive coverage of drug therapy for special populations to alert you to special considerations based on age, pregnancy, race and other factors. A separate chapter on “Complementary and Alternative Therapies discusses the available complementary and alternative modalities, including detailed information on actions, uses, and interactions of commonly used herbs. Drug Overview tables at the beginning of each chapter outline the classifications of drugs discussed and provide a handy reference of drug classes and subclasses, generic names, and trade names. Clinical Alerts highlight essential information that primary care providers must remember in order to avoid serious problems, including cautions for prescribing, information about drug interactions, or warnings about particularly ominous adverse effects. An entire unit covers drugs for health promotion to introduce you to drugs commonly seen in outpatient primary care settings and to prepare you for practice in a society increasingly focused on health promotion and disease prevention. Includes separate chapters on Immunizations and Biologicals, Weight Management, Smoking Cessation, Vitamins and Minerals, Over-the-Counter Medications, and Complementary and Alternative Therapies.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

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A Comprehensive Guide to Toxicology in Nonclinical Drug Development by Ali S. Faqi Book Summary:

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

Concise Clinical Pharmacology

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Concise Clinical Pharmacology by Ben Greenstein,Adam Greenstein Book Summary:

This is a concise study guide and thorough introduction to clinical pharmacology from which students can gain a rapid understanding of individual topics within the discipline, and from which they can review and revise certain topics before exams. This is achieved through self-contained two-page "spreads" for each topic, with concise text on the left and a diagram on the right to elaborate and reinforce the text. To further underpin the text, additional two page spreads have been included where appropriate, with case histories on the left and Q&As on the right. The text has a strong clinical focus and, in the main, sections relate to particular body systems or the therapy of a disease-class (eg, cancer). Pharmacological principles and mechanisms are covered, but the main focus is on the therapeutic use of the drugs. Sections cover basic principles of pharmacology, specialised pharmacology (inc. in pregnancy, paediatrics, geriatrics), and the vitamins. The text has been written primarily for pharmacy students, but will also be of interest to clinical medical students. The strong clinical focus should also appeal to practitioners.

Pharmacology and Medicines Management for Nurses E-Book

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Pharmacology and Medicines Management for Nurses E-Book by George Downie,Jean Mackenzie,Arthur Williams,Caroline Milne Book Summary:

This title is directed primarily towards health care professionals outside of the United States. An understanding of medicines and their effects on patients remains a crucial area of nursing knowledge. This book provides a thorough foundation upon which nurses can build their clinical experience to achieve competence. It not only provides information on the actions of drugs on the body but also gives clear guidance on the practical aspects of medicines management in both hospital and community. Organisation of the text broadly follows the British National Formulary for ease of use. Management of medicines linked to their therapeutic use Medicine administration linked with relevant care of patients where possible Basic principles of clinical pharmacology underpin the therapeutic chapters A chapter on the role of patients and carers is included All content revised in the light of changes in drug therapy, clinical practice and medicines management including nurse prescribing Key objectives for each chapter Self-assessment exercises with answers More detail relating to palliative care; nurse prescribing A new section on Intensive Therapy Totally redesigned in two colours with improved design and page layout, and better illustrations

Drug Synthesis Book Set

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Drug Synthesis Book Set by Jie Jack Li,Douglas S. Johnson Book Summary:

This set presents the authoritative and acclaimed Drug Synthesis books edited by Jie Jack Li and Douglas Johnson: Contemporary Drug Synthesis, The Art of Drug Synthesis, Modern Drug Synthesis, and Innovative Drug Synthesis. This book set will be enormously useful to pharmaceutical industry labs, research scientists in lead optimization and process development, and graduate students and courses in organic chemistry, synthetic organic chemistry, heterocyclic chemistry, medicinal chemistry, and drug synthesis courses.